TY - JOUR AU - null, PY - 2012/09/01 Y2 - 2024/03/29 TI - Acute Lymphoblastic Leukemia Complicated by Acute Severe Asthma - A Rare Finding: : A Case Report JF - African Journal of Tropical Medicine and Biomedical Research JA - AJTMBR VL - 1 IS - 4 SE - CASE REPORTS DO - UR - https://ajtmbr.org.ng/index.php/home/article/view/35 SP - 110-113 AB - <div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><strong>Introduction :</strong> The leukaemias are a group of disorders characterized by the accumulation of malignant white cells in the bone marrow and blood. These abnormal cells cause symptoms because of bone marrow failure and infiltration of organs; but acute severe asthma has not been reported as one of the manifestations/complications of acute lymphoblastic leukemia.</p><p><strong>Objective:</strong> The aim of this paper is to briefly review the literature on acute lymphoblastic leukemia and its clinicopathologic relationship with asthma. A case of Acute Lymphoid leukemia being complicated by acute severe asthma is also reported.</p><p><strong>Method/Result:</strong> I present a 36-year old male welder who came to the hospital with anaemic heart failure, leucocytosis and thrombocytopenia. Final diagnosis of acute lymphoblastic leukemia was made following bone marrow aspiration cytology and was subsequently commenced on chemotherapy. After successful Induction and Consolidation therapy, the patient had Acute Severe Asthmatic attack during the maintenance therapy and subsequently died in the hospital.</p><p><strong>Conclusion:</strong> Acute Lymphoblastic Leukemia can be complicated by acute severe asthma. Early diagnosis and use of genuine cytotoxic drugs will go a long way to ameliorate the complications of Acute leukemia.gs gave variable results. Local injections with lidocaine were also successful. Refractory cases had surgical decompression.</p><p><strong>Conclusion:</strong> Entrapment neuropathies were common conditions prevented by early identification and treatment.</p></div></div></div> ER -