Effect of Occupational exposure to Gasoline on Reproductive and Thyroid hormones among male Petrol station attendants in Kwara State

Authors

  • Adunmo Godwin Olawoyin Department of Medical Laboratory Science, Faculty of Basic Clinical Science, University of Ilorin https://orcid.org/0000-0001-7938-8092
  • Sabinari Isaiah Woru University of Ilorin https://orcid.org/0000-0002-0230-7511
  • Eyitayo O Adunmo Department of Family Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria
  • Seyi Taiwo
  • Ibrahim Muniru
  • Busari, A. O.

DOI:

https://doi.org/10.4314/ajtmbr.v6i1.1

Keywords:

BTEX, Thyroid, Petrol, testosterone

Abstract

Introduction: Petrol fume contain organic compounds that have been suggested to be endocrine

disruptors. There is paucity of data on petrol fume-linked health challenges in Nigeria. Thus, we evaluated

the effects of petrol fume exposure on blood levels of reproductive and thyroid hormones among petrol

pump station attendants in Kwara state, Nigeria.

Material and Methods: Eighty (80) petrol station attendants and fifty (50) non-occupationally exposed

subjects were recruited as controls. Anthropometric indices were taken and fasting blood samples were

collected after signing the consent form. Free triiodothyronine (FT3), free thyroxine (FT4), thyroid

stimulating hormone (TSH), testosterone, follicle stimulating hormone and luteinizing hormone were

evaluated using standard techniques.

Results: Average age and BMI of petrol fume-exposed subjects are 27.40±0.419 and 24.98±0.254

respectively and was not different from controls. Elevated FT3 and FT4 were evaluated with a decreased

TSH level in the exposed group when compared with controls. In contrast, FSH, LH and testosterone

were significantly reduced in exposed group when compared with control.

Conclusion: The result of this study shows that petrol fume toxicants adversely alter thyroid and gonadal

functions thereby modulating circulating levels of reproductive and thyroid hormones in male petrol

station attendants in Kwara state.

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Published

15-09-2023

How to Cite

1.
Adunmo GO, Sabinari I, Adunmo EO, Taiwo S, Muniru I, Busari AO. Effect of Occupational exposure to Gasoline on Reproductive and Thyroid hormones among male Petrol station attendants in Kwara State. AJTMBR [Internet]. 2023 Sep. 15 [cited 2024 Feb. 24];6(1):6-11. Available from: https://ajtmbr.org.ng/index.php/home/article/view/73